yjiB [2017-8-11 16:0:3]

cytochrome P450, monooxygenase CYP109B1

locus: BSU12210

pI: 5.38

mw: 44.83 kDa

protein length: 396 aa

gene length: 1188 bp

function: oxidation of fatty acids

product: monooxygenase CYP109B1

essential: no

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.3|Electron transport/ other]
• [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.3|Lipid metabolism/ other]

Gene

Coordinates: 1,291,344 → 1,292,534

The protein

Catalyzed reaction/ biological activity

• oxidation of saturated fatty acids (conversion up to 99%) and their methyl and ethyl esters (conversion up to 80%) at subterminal positions with a preference for the carbon atoms C11 and C12 counted from the carboxyl group [Pubmed|20186410]

Protein family

• [SW|cytochrome P450] family (according to Swiss-Prot)

Structure

• [PDB|4RM4] [Pubmed|25587700]

Expression and Regulation

Operons

• genes: [gene|D8E72C2523D5E6214C9CBAC2C1B27EA45378E162|yjiB]-[gene|02927D2CC9F44B99DB307DDFED2DD52DE2196120|yjiC]
  description: [pubmed|22383849]

  sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [pubmed|26577401], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]

  regulation

  • induced by stress ([protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]) [pubmed|26577401]

Biological materials

Mutant

• MGNA-A349 (yjiB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/349 NBRP B. subtilis, Japan]

References

• 19591681,20186410,25587700,22383849